Drug Development Pipeline

Identifying Targets and Therapies

In the past, few companies have invested in chronic and recurrent acute pancreatitis therapies, in part because researchers did not know what was causing the inflammation of the pancreas. Now, scientists are learning more about what causes the inflammation in many patients. When we know what biological processes are going wrong (called “targets”), researchers can work to identify therapies that will correct the problem.

Treatment Pipeline

TargetTherapyTarget DiscoveryTherapeutic DiscoveryPreclinical ResearchClinical ResearchStatus
Vitamin D ReceptorParicalcitolRecruiting
Pain LacosamideRecruiting
TRPV1Stem CellsRecruiting
Fibrosis/CCK ReceptorProglumide
FibrosisPirfenidone
IL-6Tocilizumab
Inflammation/Flare-upsSimvastatin
CFTRIvacaftor, MC 007
PRSS1Gene Therapy
TrypsinTrypsin Antibody
T3DStem Cells
PainChemical Pancreatectomy
SPINK1Engineered protein
FGF21MC 017

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