High triglyceride levels can affect people in different ways. High triglycerides often don’t cause symptoms, so many people don’t realize their levels are elevated until a blood test. When triglycerides get extremely high, they can sometimes cause physical signs (like small yellow skin bumps) and can raise the risk of serious complications, including acute pancreatitis and other long-term health risks.Â
For people trying to understand what high triglycerides mean for their health and how to manage them day to day, finding reliable information, peer connection, and support through mutual sharing can be challenging.
What is ‘High Triglycerides Connect’?
Inspire, an online health community platform, recently launched High Triglycerides Connect, with support from Ionis. This free, online group is intended for people living with high triglyceride levels and their care partners or caregivers.
The space offers an opportunity to:
- Connect with others living with high triglycerides
- Share experiences and ask questions
- Learn from peer perspectives on lifestyle changes and treatmentÂ
- Talk about the emotional and practical challenges of navigating a condition that is often invisible until a health scare, and may not be very well understood
This group can offer a place where people can feel seen and heard and find opportunities to share with and learn from peers.Â
The information you share in this community will have all personal details removed to protect your privacy. This de-identified information will be shared with Ionis Pharmaceuticals to help them better understand the experiences of people with high triglycerides and FCS. These insights can help guide their research, product development, and clinical plans.Â
Why It Matters
Managing high triglycerides often requires long-term lifestyle modifications and medical decisions, and having access to clear information and support can make that process feel less overwhelming.
For people whose pancreatitis is linked to high triglyceride levels, Mission: Cure offers educational resources focused specifically on pancreatitis and the connection to high triglycerides, including:
- Triglycerides & Pancreatitis Webinar: A patient-focused discussion on how very high triglyceride levels can contribute to pancreatitis, what testing and monitoring may involve, treatment options for Familial Chylomicronemia Syndrome, and options in development for high triglyceride levels, and questions to discuss with your healthcare team.
- Triglycerides & FCS Resource Page: An overview of hypertriglyceridemia and Familial Chylomicronemia Syndrome (FCS), how they relate to pancreatitis, and what the research says, and available FDA-approved treatment options.
These resources are designed to support patients and families with clear information, whether you’re newly diagnosed or navigating long-term care.
Recent News from Ionis
Ionis announced results from a study of olezarsen for people with severe hypertriglyceridemia (sHTG). The study results were presented during the American Heart Association Scientific Sessions as a late-breaking clinical trial.
You can read the full announcement here:
On December 1, 2025, Ionis also announced that the U.S. FDA granted Breakthrough Therapy designation for olezarsen for severe hypertriglyceridemia (sHTG).
About Mission: Cure
At Mission: Cure, we are dedicated to finding effective treatments and, ultimately, a cure for pancreatitis. Through patient education, research, and advocacy, we strive to improve the lives of those affected by this condition.
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