Treatments

Welcome to Mission: Cure’s collection of resources on pancreatitis treatment options. Here, you’ll find articles covering various approaches—from medical therapies to lifestyle adjustments and emerging treatments—designed to help manage symptoms and enhance quality of life for those affected by pancreatitis. Explore the latest insights and updates to stay informed on ways to improve care and support.

FDA Approves New Treatment for Familial Chylomicronemia Syndrome (FCS)

We have some exciting news for people living with pancreatitis caused by the FCS genetic mutation. The FDA has approved REDEMPLO® (plozasiran), a new treatment from Arrowhead Pharmaceuticals that lowers triglycerides and reduces acute pancreatitis attacks in adults with Familial Chylomicronemia Syndrome (FCS). This is an important step for people with FCS and a meaningful […]

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New Resource: Managing Life with FCS – A Peer Support Toolbox

High triglycerides are one of the leading causes of pancreatitis, and for some people, extremely high levels can be caused by a rare genetic condition called Familial Chylomicronemia Syndrome (FCS). We’re excited to share a new resource created for and by the FCS community in partnership with Arrowhead Pharmaceuticals. This was specifically designed for people

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The Risks of Steroid Use for Type 1 Autoimmune Pancreatitis (IgG4-RD)

For people living with IgG4-Related Disease (IgG4-RD), treatment can be complicated. The disease is rare, often misdiagnosed, and can affect many different organs. When it affects the pancreas, it is called Type 1 Autoimmune Pancreatitis (AIP). Steroids are usually the first treatment doctors prescribe because they quickly reduce inflammation, improve symptoms, and induce remission, and

The Risks of Steroid Use for Type 1 Autoimmune Pancreatitis (IgG4-RD) Read More »

blog feature image with IV bag and text 'first fda-approved treatment for Igg4-RD'

FDA Approves First-Ever Treatment for IgG4-Related Disease: What This Means for People With Type 1 AIP and Beyond

On April 3, 2025, the FDA approved Uplizna® (inebilizumab-cdon) as the first and only approved treatment for Immunoglobulin G4-related disease (IgG4-RD), the condition behind Type 1 Autoimmune Pancreatitis (AIP). This is a huge milestone. It’s the first time a treatment has been officially approved for this rare, immune-related cause of pancreatitis. For patients living with

FDA Approves First-Ever Treatment for IgG4-Related Disease: What This Means for People With Type 1 AIP and Beyond Read More »

Self injector of Familial Chylomicronemia Syndrome (FCS) treatment drug, TRYNGOLZA (olezarsen).

FDA Approves First-Ever Treatment for Familial Chylomicronemia Syndrome (FCS)

Exciting news! The U.S. Food and Drug Administration (FDA) has approved TRYNGOLZA (olezarsen), developed by Ionis, as the first-ever treatment for Familial Chylomicronemia Syndrome (FCS). FCS is a rare genetic condition that causes dangerously high triglyceride levels, increasing the risk of severe health complications–especially pancreatitis. This approval is a major milestone—not just for people with

FDA Approves First-Ever Treatment for Familial Chylomicronemia Syndrome (FCS) Read More »

Image of a scientist doing research on a clinical trial.

New Clinical Trial Testing a Repurposing Drug, Proglumide, Aims to Treat Pain in Chronic Pancreatitis

Acute pancreatitis, a life-threatening condition, occurs suddenly and is often idiopathic (meaning, for unknown reasons). Although treatment specific to the disease is lacking, it usually resolves with proper clinical management. Multiple episodes may occur over time, leading to recurrent acute pancreatitis, which can eventually lead to chronic pancreatitis. Chronic pancreatitis is irreversible inflammatory and fibrotic

New Clinical Trial Testing a Repurposing Drug, Proglumide, Aims to Treat Pain in Chronic Pancreatitis Read More »

Image of Mission: Cure staff at Pancreasfest

Getting Ready to Test New Pancreatitis Treatments: News from PancreasFest

When will we have new treatments for pancreatitis? In July, Mission: Cure met with researchers and doctors to discuss this important question. Mission: Cure CEO Megan Golden, VP for Translational Research Lola Rahib, and the summer interns attended PancreasFest 2022 at the University of Pittsburgh. PancreasFest is an annual conference that brings together researchers who

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New Collaboration with Johns Hopkins to Treat Pancreatitis Pain

Mission: Cure has provided initial funding to Johns Hopkins Medicine to launch the new Pancreatitis Pain Research Center. Mission: Cure will work with Johns Hopkins to establish the Pancreatitis Pain Research Program. The goals for the pancreatitis pain program are: To study and treat specific types of pain associated with chronic pancreatitis To create an

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Image of John Mellnik, CEO of Path BioAnalytics (PBA) with the text "Webinar" in the upper left corner and "New Therapies For Pancreatitis" in the middle.

New Therapies for Pancreatitis

Webinar: “New Therapies For Pancreatitis” https://youtu.be/I7XM-fdapvs Mission: Cure’s webinar on February 23rd, 2022 featured three biotech executives who are searching for a cure for pancreatitis and one of its major complications, diabetes. John Mellnik, CEO of Path BioAnalytics (PBA), discusses their most recent project that uses translational science and proprietary technology to identify drugs that

New Therapies for Pancreatitis Read More »

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