Ionis

Ionis announces FDA approval of a treatment for severe hypertriglyceridemia (sHTG)

On June 24, 2026, Ionis Pharmaceuticals announced that the U.S. Food and Drug Administration approved TRYNGOLZA (Olezarsen) to lower triglycerides and reduce the risk of acute pancreatitis in adults with severe hypertriglyceridemia. 

This treatment was previously approved for Familial Chylomicronemia Syndrome (FCS), a rare genetic form of severe hypertriglyceridemia. This approval expands its use to adults with severe hypertriglyceridemia.

Read the official Ionis press release for complete details: https://ir.ionis.com/news-releases/news-release-details/tryngolzar-olezarsen-approved-fda-first-and-only-treatment 

To learn more about high triglycerides, severe hypertriglyceridemia, and pancreatitis, watch our webinar with Dr. Andres Gelrud: High Triglycerides & Pancreatitis: Causes, Diagnosis & Treatments

Read more about Triglycerides, sHTG, FCS, and Pancreatitis on our webpage.

About Mission: Cure

At Mission: Cure, we are dedicated to finding effective treatments and, ultimately, a cure for pancreatitis. Through patient education, research, and advocacy, we strive to improve the lives of those affected by this condition.

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